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dc.contributor.authorBliman, Pierre-Alexandre
dc.contributor.authorAronna, Maria Soledad
dc.contributor.authorCoelho, Flávio Codeço
dc.contributor.authorSilva, Moacyr da
dc.date.accessioned2017-04-11T12:20:34Z
dc.date.available2017-04-11T12:20:34Z
dc.date.issued2015-03-19
dc.identifier.urihttp://hdl.handle.net/10438/18169
dc.description.abstractThe control of the spread of dengue fever by introduction of the intracellular parasitic bacterium Wolbachia in populations of the vector Aedes aegypti, is presently one of the most promising tools for eliminating dengue, in the absence of an efficient vaccine. The success of this operation requires locally careful planning to determine the adequate number of individuals carrying the wolbachia parasite that need to be introduced into the natural population. The introduced mosquitoes are expected to eventually replace the Wolbachia-free population and guarantee permanent protection against the transmission of dengue to human. In this study, we propose and analyze a model describing the fundamental aspects of the competition between mosquitoes carrying Wolbachia and mosquitoes free of the parasite. We then use feedback control techniques to devise an introduction protocol which is proved to guarantee that the population converges to a stable equilibrium where the totality of mosquitoes carry Wolbachia.eng
dc.language.isoeng
dc.publisherEMAppor
dc.subjectWolbachiaeng
dc.subjectGlobal stabilizationeng
dc.subjectMonotone systemseng
dc.subjectInput-output characteristiceng
dc.titleEnsuring successful introduction of Wolbachia in natural populations of Aedes aegypti by means of feedback controleng
dc.typeWorking Papereng
dc.subject.areaSaúdepor
dc.contributor.unidadefgvEscolas::EMAppor
dc.contributor.unidadefgvRede de Pesquisapor
dc.subject.bibliodataArbovirosespor
dc.subject.bibliodataDenguepor
dc.subject.bibliodataAedes aegyptipor
dc.subject.bibliodataChikungunyapor
dc.subject.bibliodataWolbachiapor


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